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Living organisms have different sensitivities to toxicants. This variability can be represented by constructing a species sensitivity distribution (SSD) curve which allows calculating the Hazard Concentration HC5, that is, the concentration at which 5% of the considered species are affected. The ShinySSD web application serves to simultaneously model the SSD curve of a user-defined toxicity dataset based on four different statistical distribution models and calculates three estimators HC1, HC5, and HC10 with its confidence intervals.